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A deficiency occurs if a person doesn't get enough vitamin D from sunlight or food, or if their body can't synthesize or absorb vitamin D properly due to an underlying condition or medication.
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
Levels of DHEA-S in circulation are approximately 250 to 300 times those of DHEA. [20] DHEA-S in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). [54] [55] The terminal half-life of DHEA is short at only 15 to 30 minutes. [56] In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56]
How much vitamin D to take. Most of us — healthy adults between 19 and 70 — should try to consume 600-800 IUs, says Haggans ...
A meta-analysis from 2020 also found that vitamin D deficiency may be ... (DHEA). This hormone is a ... to vitamins as a “proven” ED treatment: Vitamins like B3, B9, C and D are important for ...
Vitamin D deficiency is associated with increased mortality in critical illness. [49] People who take vitamin D supplements before being admitted for intensive care are less likely to die than those who do not take vitamin D supplements. [49] Additionally, vitamin D levels decline during stays in intensive care. [50]
DHEA and DHEA-S are the most abundant circulating steroids in the body. [29] Plasma levels of DHEA-S are 100 or more times higher than those of DHEA, 5 to 10 times higher than those of cortisol, 100 to 500 times those of testosterone, and 1,000 to 10,000 times higher than those of estradiol. [30] [3] Levels of DHEA and DHEA-S vary throughout life.
The UK National Health Service (NHS) recommends that people at risk of vitamin D deficiency, breast-fed babies, formula-fed babies taking less than 500 ml/day, and children aged 6 months to 4 years, should take daily vitamin D supplements throughout the year to ensure sufficient intake. [56]