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Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. [1] Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. [1] Other symptoms may include bone pain, chest pain, or itchiness. [1]
Primary cutaneous diffuse large B-cell lymphoma, leg type is an aggressive B-cell lymphoma that is often resistant to therapy and carries a poor prognosis, [5] i.e., they have a 5-year disease-specific survival rate of 43% or 70% depending on whether their cancer cells have or do not have, respectively, inactivating mutations in both of their ...
Mantle cell lymphoma (MCL) is a type of non-Hodgkin's lymphoma, comprising about 6% of cases. [1] [2] It is named for the mantle zone of the lymph nodes where it develops.[3] [4] The term 'mantle cell lymphoma' was first adopted by Raffeld and Jaffe in 1991.
Subtypes of T-cell lymphoma [1]. Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), is a subtype of peripheral T-cell lymphoma.Peripheral T-cell lymphoma (PTCL) is defined as a diverse group of aggressive lymphomas that develop from mature-stage white blood cells called T-cells and natural killer cells (see figure for an overview of PTCL subtypes).
In a review study of 26 patients (i.e., 15 men and 11 women, median age 72 years, range from 44 to 90 years) diagnosed with Lennert lymphoma: a) 7 presented with B symptoms (i.e., fever, night sweats, and/or unintentional weight loss); b) 8 presented with (or later acquired) cancer cells in their bone marrow, blood, skin, liver, lung, bone, and ...
Nodular sclerosing Hodgkin lymphoma ("NSHL") or Nodular sclerosis is a form of Hodgkin's lymphoma [1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years.
Complete surgical resection and/or radiation therapy are used to treat primary cutaneous anaplastic large cell lymphoma as a single lesion; the majority of patients experience total remission. [7] While radiation of the primary lesion and the surrounding lymph nodes has been advised for patients whose local lymph nodes are involved, adding ...
Romidepsin, vorinostat and a few others are a second-line drug for cutaneous T-cell lymphoma. [17] Mogamulizumab has been approved in Japan [18] and the United States. [19] The FDA has approved denileukin diftitox-cxdl (Lymphir) for the treatment of patients with relapsed/refractory cutaneous T-cell lymphoma (CTCL) after at least 1 prior ...