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Intimacy Problems. Sertraline and other SSRIs can cause a variety of intimacy side effects, from difficulty climaxing to decreased drive. ... so its concentration will be reduced by the time you ...
Sertraline is highly plasma protein bound (98.5%) across a concentration range of 20 to 500 ng/mL. [5] Despite the high plasma protein binding, sertraline and its metabolite desmethylsertraline at respective tested concentrations of 300 ng/mL and 200 ng/mL were found not to interfere with the plasma protein binding of warfarin and propranolol ...
SSRIs can cause various types of sexual dysfunction such as anorgasmia, erectile dysfunction, diminished libido, genital numbness, and sexual anhedonia (pleasureless orgasm). [49] Sexual problems are common with SSRIs. [50] Poor sexual function is one of the most common reasons people stop the medication. [51]
Chronic anxiety can be treated — and treating it can help your brain health. Mood issue #2: Feeling depressed Lots of everyday things can put you in a bad mood.
Higher dosage does, however, increase the incidence and severity of adverse events associated with excessive 5-HT re-uptake inhibition. [6] Figure 2 Inhibition of re-uptake transport proteins, e.g. SERT, results in increased concentration of neurotransmitters, e.g. 5-HT, in the synaptic cleft, leading to improvement of depression symptoms
Switching to a new type of antidepressant may help reverse any weight gain you’ve experienced during treatment. Research shows that approximately one-third of people with depression have ...