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  2. Electrostatic discharge - Wikipedia

    en.wikipedia.org/wiki/Electrostatic_discharge

    A charged device model (CDM) test is used to define the ESD a device can withstand when the device itself has an electrostatic charge and discharges due to metal contact. This discharge type is the most common type of ESD in electronic devices and causes most of the ESD damages in their manufacturing.

  3. Excitotoxicity - Wikipedia

    en.wikipedia.org/wiki/Excitotoxicity

    Glutamate is a prime example of an excitotoxin in the brain, and it is also the major excitatory neurotransmitter in the central nervous system of mammals. [14] During normal conditions, glutamate concentration can be increased up to 1 mM in the synaptic cleft , which is rapidly decreased in the lapse of milliseconds. [ 15 ]

  4. Neurotoxicity - Wikipedia

    en.wikipedia.org/wiki/Neurotoxicity

    Aβ was found manipulating the level of nicotine in the brain along with the MAP kinase, another signaling receptor, to cause cell death. Another chemical in the brain that Aβ regulates is JNK; this chemical halts the extracellular signal-regulated kinases (ERK) pathway, which normally functions as memory control in the brain. As a result ...

  5. Toxic encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_encephalopathy

    Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...

  6. Brain ischemia - Wikipedia

    en.wikipedia.org/wiki/Brain_ischemia

    Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.

  7. Brain injury - Wikipedia

    en.wikipedia.org/wiki/Brain_injury

    The brain damage caused by radiation depends on where the brain tumor is located, the amount of radiation used, and the duration of the treatment. Radiosurgery can also lead to tissue damage that results in about 1 in 20 patients requiring a second operation to remove the damaged tissue.

  8. Reperfusion injury - Wikipedia

    en.wikipedia.org/wiki/Reperfusion_injury

    In rats, it has been shown that neurons often die a full 24 hours after blood flow returns. Some theorize that this delayed reaction derives from the various inflammatory immune responses that occur during reperfusion. [11] These inflammatory responses cause intracranial pressure, pressure which leads to cell injury and in some situations cell ...

  9. Failure of electronic components - Wikipedia

    en.wikipedia.org/wiki/Failure_of_electronic...

    Electrostatic discharge (ESD) is a subclass of electrical overstress and may cause immediate device failure, permanent parameter shifts and latent damage causing increased degradation rate. It has at least one of three components, localized heat generation, high current density and high electric field gradient; prolonged presence of currents of ...

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