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In genetics, a locus (pl.: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. [1] Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at ...
Genetic markers have to be easily identifiable, associated with a specific locus, and highly polymorphic, because homozygotes do not provide any information. Detection of the marker can be direct by RNA sequencing, or indirect using allozymes.
In addition to scholarly work on Early Modern Europe, genealogy, The Melungeons, and bibliographic work in early US history, DeMarce has written or co-authored a number of formative short stories and novels in the 1632 series collaborative fiction project. She is one of the principal controlling parties of the collaboration, and a member of the ...
Coalescent theory is a model of how alleles sampled from a population may have originated from a common ancestor.In the simplest case, coalescent theory assumes no recombination, no natural selection, and no gene flow or population structure, meaning that each variant is equally likely to have been passed from one generation to the next.
The specific location of a DNA sequence within a chromosome is known as a locus. If the DNA sequence at a particular locus varies between individuals, the different forms of this sequence are called alleles. DNA sequences can change through mutations, producing new alleles. If a mutation occurs within a gene, the new allele may affect the trait ...
The frequency of new mutations at a particular locus or in a particular gene, sequence, genome, or organism over a specified period of time, e.g. during a single generation. Mutation rates may be calculated for a specific class of mutation or for all types collectively; they vary widely by organism and with an organism's environment.