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This article covers the histology of lymph nodes, including zones, their characteristics, cell types, and clinical aspects. Learn this topic now at Kenhub!
Lymph nodes & spleen, nonlymphoma. Authors: Nadine Aguilera, M.D., Roaa Aljuaid, M.B.B.S., Ahmed Alrajjal, M.D., João Víctor Alves de Castro, M.D., Barina Aqil, M.D., Aaron Auerbach, M.D., M.P.H., Simon A. Backer, M.D., Jayalakshmi Balakrishna, M.D., Amy Beckman, M.D., Jacob Bledsoe, M.D., Laura Brown, M.D., Ryanne A. Brown, M.D., M.B.A ...
Scattered throughout the body, lymph nodes perform the critical function of filtering both exogenous and endogenous antigens and producing immune response through activated lymphocytes and antibodies. They can become enlarged in infections, autoimmune diseases, lymphomas, and metastatic carcinomas. [1]
Lymph nodes are important for the body's immune system. They are small, bean-shaped, encapsulated organs that are found throughout the body, most often in the neck, groin, and underarms. Lymph nodes are made up of clusters of lymphocytes and other white blood cells that help fight infection.
Lymph nodes are small organs interposed along lymphatic vessels that immunologically monitor lymph. Capsule - dense connective tissue enclosing the node. Subcapsular Sinus - space underneath the capsule that receives lymph from afferent lymphatic vessels.
What are lymph nodes? These are about 100-200 100 bean shaped organs, which are found along lymphatic vessels, and which filter micro-organisms etc from lymph. This is a diagram of a lymph node , cut away to show the organisation inside, into cortical and medullary regions.
Lymph nodes are secondary lymphoid organs and play a central role in the body's immune defense. They consist of an outer capsule made of collagenous connective tissue, from which trabeculae or septa extend into the body of the node, which divide the organ into compartments.
Understanding the histomorphologic features of the lymphoid lobule and the role of the reticular meshwork scaffolding of the lymph node and how these related to the cortex, paracortex and medulla provides a unique approach to understanding lymph node structure and function.
This 1-year experience demonstrated that the normal lymph node tutorial can be used as an effective adjunct in educating pathology residents and medical students on normal lymph node cytomorphology and immunoarchitecture in the context of a busy clinical patient care setting.
Histology of lymph nodes (capsule, cortex, medulla) and nodules, high endothelial venules, and macrophages with lipofuscin.