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Schizophrenia is a mental disorder [17] [7] characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, [10] and flat or inappropriate affect. [7]
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
Schizophreniform disorder is a type of mental illness that is characterized by psychosis and closely related to schizophrenia.Both schizophrenia and schizophreniform disorder, as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), have the same symptoms and essential features except for two differences: the level of functional impairment and the duration of symptoms.
'This will turn out to be the most important break in the disease,' the Broad Institute's director Eric Lander said.
Diagnosis of schizophrenia from non-psychotic disorders Sensitivity 61.8 (51.7, 71.0) Specificity 94.1 (88.0, 97.2) 55% (19% to 89%) With a prevalence of 55%, 55 out of every 100 people with non-psychotic disorders will have schizophrenia. Of these, 21 will not be identified as having schizophrenia by use of FRS (38% of 55).
Research on rodents seeking to understand the possible role of prenatal hypoxia in disorders such as schizophrenia has indicated that it can lead to a range of sensorimotor and learning/memory abnormalities. Impairments in motor function and coordination, evident on challenging tasks when the hypoxia was severe enough to cause brain damage ...
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