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  2. Amoxicillin/clavulanic acid - Wikipedia

    en.wikipedia.org/wiki/Amoxicillin/clavulanic_acid

    Amoxicillin is an antibiotic while clavulanic acid is a non-antibiotic β-lactamase inhibitor which prevents metabolism of amoxicillin by certain bacteria. In addition to its β-lactamase inhibition, clavulanic acid shows central nervous system actions and effects and has been studied in the potential treatment of various psychiatric and ...

  3. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    For example, Augmentin (FGP) is made of amoxicillin (a β-lactam antibiotic) and clavulanic acid (a β-lactamase inhibitor). The clavulanic acid is designed to overwhelm all β-lactamase enzymes, and effectively serve as an antagonist so that the amoxicillin is not affected by the β-lactamase enzymes. Another β-lactam/β-lactamase inhibitor ...

  4. Clavulanic acid - Wikipedia

    en.wikipedia.org/wiki/Clavulanic_acid

    Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic , when combined with penicillin -group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase , which otherwise inactivates most penicillins.

  5. List of β-lactam antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_β-lactam_antibiotics

    The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.

  6. Clavam - Wikipedia

    en.wikipedia.org/wiki/Clavam

    Clavulanic acid is a broad-spectrum antibiotic and 5S clavams may have anti-fungal properties. They are similar to penams, but with an oxygen substituted for the sulfur. [3] Thus, they are also known as oxapenams. An example is clavulanic acid, [4] from which this compound class receives its name. Clavulanic acid, a type of clavam, has ...

  7. Amoxicillin - Wikipedia

    en.wikipedia.org/wiki/Amoxicillin

    Amoxicillin (α-amino-p-hydroxybenzyl penicillin) is a semisynthetic derivative of penicillin with a structure similar to ampicillin but with better absorption when taken by mouth, thus yielding higher concentrations in blood and in urine. [58] Amoxicillin diffuses easily into tissues and body fluids.

  8. β-Lactamase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Β-Lactamase_inhibitor

    This is a favorable drug design over many clinically used competing agents, because most of them, such as clavulanic acid, become hydrolysed, and are therefore only useful for a finite period of time. This generally causes the need for a higher concentration of competitive inhibitor than would be necessary in an unhydrolyzable inhibitor.

  9. Combination antibiotic - Wikipedia

    en.wikipedia.org/wiki/Combination_antibiotic

    A combination antibiotic is one in which two ingredients are added together for additional therapeutic effect. [1] One or both ingredients may be antibiotics. [1]Antibiotic combinations are increasingly important because of antimicrobial resistance. [2]