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Common side effects include headache and vomiting. [2] Severe side effects may include kidney problems. [2] Use in pregnancy appears to be safe. [2] It is a prodrug, which works after being converted to aciclovir in a person's body. [2] Valaciclovir was patented in 1987 and came into medical use in 1995.
The recommended dosage for suppression therapy for recurrent outbreaks is 1,000 mg of valacyclovir once a day or 400 mg Acyclovir taken twice a day. In addition to preventing outbreaks, these medications greatly reduce the chance of infecting someone while the patient is not having an outbreak. [citation needed]
In 2009, acyclovir in combination with hydrocortisone cream, marketed as Xerese, was approved in the United States for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and children (six years of age and older). [61] [62]
Cold sores versus canker sores To make a true diagnosis of the cold sore virus, your doctor needs to take a culture from the area and send it to the lab for analysis, says Dr. Friedman.
Cold sore; Other names: fever blister, [1] herpes labialis, [1] oral herpes, [2] orolabial herpes [3] A cold sore on the lower lip. Note the blisters in a group marked by an arrow. Specialty: Infectious disease: Symptoms: Burning pain followed by small blisters or sores [1] Complications: Herpes encephalitis, herpetic whitlow [4] Usual onset ...
An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...