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Oral disease is one of the most common diseases found in dogs. [ 1 ] [ 2 ] It is caused by the buildup of various anaerobic bacteria in the mouth which forms plaque , eventually hardening into tartar on the teeth along the gum line, and is related to the development of gingivitis . [ 3 ]
The C2DA inhibit methicillin resistant staphylococcus biofilm, but don't eliminate it. The mechanism of the biofilm inhibition by these molecules is still unknown. C2D is a medium of fatty acid chain that effect on staphylococcus aureus biofilm and dispersion of these biofilm. Pseudomonas aeruginosa is the main source for these molecules. [15]
Researchers from Ben-Gurion University of the Negev, in collaboration with teams from Sichuan University and the National University of Singapore, have identified that 3,3′-Diindolylmethane (DIM) – a naturally occurring molecule also referred to as bisindole – can reduce biofilms responsible for plaque and cavities by a remarkable 90%. [7]
It is taken by mouth. [3] Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of medications. [3]
The mouth contains a wide variety of oral bacteria, but only a few specific species of bacteria are believed to cause dental caries: Streptococcus mutans and Lactobacillus species among them. Streptococcus mutans are gram-positive bacteria which constitute biofilms on the surface of teeth.
A denture cleaner (also termed denture cleanser) is used to clean dentures when they are out of the mouth. The main use is to control the growth of microorganisms on the dentures, especially Candida albicans, thereby preventing denture-related stomatitis. When dentures are worn in the mouth, a biofilm develops which may be similar to dental plaque.