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THC morpholinylbutyrate (SP-111, Δ 9-THC-O-[4-(morpholin-4-yl)butyrate]) is a synthetic derivative of tetrahydrocannabinol, developed in the 1970s.It is a prodrug which is converted into THC inside the body, and was one of the first derivatives of THC that is able to form water-soluble salts, giving it a significant advantage over THC for some applications.
Although the chemical formula for THC (C 21 H 30 O 2) describes multiple isomers, [10] the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ 9-tetrahydrocannabinol. It is a colorless oil.
Samples seized across the United States by the Drug Enforcement Administration over an 18-year period (1980–1997) showed that THC content in hashish and hashish oil averaging 12.9% and 17.4%, respectively, did not show an increase over time. [7] The highest THC concentrations measured were 52.9% in hashish and 47.0% in hash oil. [8]
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THC hemisuccinate (Δ 9-THC-O-hemisuccinate, Dronabinol hemisuccinate) is a synthetic derivative of tetrahydrocannabinol, developed in the 1990s.It is a water-soluble prodrug ester which is converted into THC inside the body, and was developed to overcome the poor bioavailability of THC when taken by non-inhaled routes of administration.
Tetrahydrocannabinol (THC) is the primary psychoactive component of the Cannabis plant. Delta-9-tetrahydrocannabinol (Δ 9-THC, THC) and delta-8-tetrahydrocannabinol (Δ 8-THC), through intracellular CB 1 activation, induce anandamide and 2-arachidonoylglycerol synthesis produced naturally in the body and brain [citation needed] [dubious ...
Δ 9-Tetrahydrocannabutol (tetrahydrocannabinol-C4, THC-C4, Δ 9-THCB, (C4)-Δ 9-THC, butyl-THC) is a phytocannabinoid found in cannabis that is a homologue of tetrahydrocannabinol (THC), the main active component of Cannabis. [1] Structurally, they are only different by the pentyl side chain being replaced by a butyl side chain.
Under the 2018 Agriculture Improvement Act (Farm Bill), hemp-derived cannabinoids, including Delta 10 THC, are federally legal if they contain less than 0.3% Delta 9 THC.