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Squamous-cell carcinoma is a cancer of the squamous cell, a kind of epithelial cell found in both the skin and mucous membranes. It accounts for over 90% of all head and neck cancers, [ 89 ] including more than 90% of throat cancer. [ 22 ]
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
In 2015, squamous cell cancer of the head and neck region was the fifth most common cancer other than skin cancer, globally, with an annual incidence of 600,000 cases and about 60,000 cases annually in the United States and Europe. [218] The global incidence of pharyngeal cancer in 2013 was estimated at 136,000 cases.
Carcinoma of the tonsil is a type of squamous cell carcinoma. The tonsil is the most common site of squamous cell carcinoma in the oropharynx. It comprises 23.1% of all malignancies of the oropharynx. [1] The tumors frequently present at advanced stages, and around 70% of patients present with metastasis to the cervical lymph nodes. [2].
type 1: squamous cell carcinoma, typically found in older adults; type 2: non-keratinizing carcinoma; type 3: undifferentiated carcinoma; Type 3 is most commonly found among younger children and adolescents, with a few type 2 cases. Both type 2 and 3 have been found to be associated with elevated levels of Epstein-Barr virus titers, but not type 1.
John Michael Murdoch went to Oregon Health & Science University to undergo a tracheostomy — to install a breathing hole in his neck — in December 2022 as part of a treatment plan for squamous ...
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