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Preclinical imaging is the visualization of living animals for research purposes, [1] such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in animals responding to physiological or environmental changes.
Preclinical SPECT is a quantitative imaging modality. The uptake of SPECT tracers in organs (regions) of interest can be calculated from reconstructed images. The small size of laboratory animals diminishes the photon’s attenuation in the body of the animal (compared to one in human-sized objects).
In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.
Bruker Sets New Standards in Preclinical Imaging Software with ParaVision 6 Higher Productivity, Increased Performance and Easy Access to MRI for Translational and Pharmaceutical Research SAVANNAH ...
Spatial Frequency Domain Imaging (SFDI) is a non-invasive optical imaging method that uses spatially modulated light to extract quantitative information about tissue properties. Its large field of view coupled with its quantitative approach to imaging has made it a novel imaging modality, with many use cases in murine pre-clinical trials.
Electron resonance imaging (ERI) is a preclinical imaging method, together with positron emission tomography (PET), computed tomography scan (CT scan), magnetic resonance imaging (MRI), and other techniques. ERI is dedicated to imaging small laboratory animals, and its unique feature is the ability to detect free radicals.
NEW YORK, Jan. 31, 2025 (GLOBE NEWSWIRE) -- Y-mAbs Therapeutics, Inc. (the “Company” or “Y-mAbs”) (Nasdaq: YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel radioimmunotherapy and antibody-based therapeutic products for the treatment of cancer, today announced the presentation of preclinical and translational pharmacokinetics ...
Magnetic particle imaging (MPI) is an emerging non-invasive tomographic technique that directly detects superparamagnetic nanoparticle tracers. The technology has potential applications in diagnostic imaging and material science .