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Saliva on a baby's lips. Saliva (commonly referred to as spit or drool) is an extracellular fluid produced and secreted by salivary glands in the mouth.In humans, saliva is around 99% water, plus electrolytes, mucus, white blood cells, epithelial cells (from which DNA can be extracted), enzymes (such as lipase and amylase), and antimicrobial agents (such as secretory IgA, and lysozymes).
The salivary gland specific genes are mainly genes that encode for secreted proteins and compared to other organs in the human body; the salivary gland has the highest fraction of secreted genes. The heterogeneous family of proline-rich, human salivary glycoproteins, such as PRB1 and PRH1 , are salivary gland-specific proteins with highest ...
Human saliva contains a wide variety of bacteria that are harmless in the mouth, but that may cause significant infection if introduced into a wound. A notable case was a diabetic man who licked his bleeding thumb following a minor bicycle accident , and subsequently had to have the thumb amputated after it became infected with Eikenella ...
It can affect any organ of the body, depressing cellular immunity and enhancing humoral immunity. Salivary gland involvement primarily involves both parotid glands, causing enlargement and swelling. Salivary gland biopsy with histopathologic examination is needed to make the distinction between whether Sjoren's syndrome or sarcoidosis is the ...
The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body.
Nitrate extracted from blood by the salivary gland, accumulates in saliva, which is then reduced to nitric oxide to have a direct blood pressure lowering effect. Decreasing saliva nitrite in volunteers that already had elevated levels, a rise in systolic and diastolic blood pressure resulted. Furthermore, pre-hypertensives may be more sensitive ...
"There is high diversity in the salivary microbiome within and between individuals, but little geographic structure. Overall, ~13.5% of the total variance in the composition of genera is due to differences among individuals, which is remarkably similar to the fraction of the total variance in neutral genetic markers that can be attributed to differences among human populations."
In human anatomy, the mouth is the first portion of the alimentary canal that receives food and produces saliva. [2] The oral mucosa is the mucous membrane epithelium lining the inside of the mouth. In addition to its primary role as the beginning of the digestive system, the mouth also plays a significant role in communication.