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Doxycycline, doxycycline monohydrate and doxycycline hyclate are yellow, crystalline powders with a bitter taste. The latter smells faintly of ethanol , a 1% aqueous solution has a pH of 2–3, and the specific rotation is [ α ] D 25 {\displaystyle [\alpha ]_{D}^{25}} −110° cm 3 /dm·g in 0.01 N methanolic hydrochloric acid .
Meta-analyses have concluded that probiotics may protect against antibiotic-associated diarrhea in both children and adults. [2] [3] Evidence is insufficient, however, regarding an effect on rates of C. difficile colitis. [4] The efficacy of probiotic AAD prevention is dependent on the probiotic strain(s) used and on the dosage.
Diarrhea is defined by the World Health Organization as having three or more loose or liquid stools per day, or as having more stools than is normal for that person. [2] Acute diarrhea is defined as an abnormally frequent discharge of semisolid or fluid fecal matter from the bowel, lasting less than 14 days, by World Gastroenterology ...
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
Infections of the lungs or urinary tract in children may also cause vomiting or diarrhea. [1] Classical diabetic ketoacidosis (DKA) presents with abdominal pain, nausea, and vomiting, but without diarrhea. [1] One study found that 17% of children with DKA were initially diagnosed as having gastroenteritis. [1]
Chronic diarrhea (alternate spelling: diarrhoea) of infancy, also called toddler's diarrhea, is a common condition typically affecting up to 1.7 billion children between ages 6–30 months worldwide every year, usually resolving by age 4.
The selection and use of essential medicines. Twentieth report of the WHO Expert Committee 2015 (including 19th WHO Model List of Essential Medicines and 5th WHO Model List of Essential Medicines for Children). Geneva: World Health Organization. 2015. hdl: 10665/189763. ISBN 978-92-4-069494-1. ISSN 0512-3054. WHO technical report series; no. 994.
A hyclate (Latin: hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate [1] [2] (·HCl· 1 / 2 EtOH· 1 / 2 H 2 O), e.g. doxycycline hyclate. [ 3 ] [ 4 ] References