Search results
Results From The WOW.Com Content Network
The alpha-2 (α 2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the G i heterotrimeric G-protein. It consists of three highly homologous subtypes, including α 2A-, α 2B-, and α 2C-adrenergic. Some species other than humans express a fourth α 2D-adrenergic receptor as well. [1]
The alpha-adrenergic receptor has two subclasses α 1 and α 2. Alpha 2 receptors are associated with sympatholytic properties. Alpha-adrenergic agonists have the opposite function of alpha blockers. Alpha adrenoreceptor ligands mimic the action of epinephrine and norepinephrine signaling in the heart, smooth muscle and central nervous system, with
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β 2) antagonists and alpha-2 (α 2) agonists, which are used to treat high ...
Alpha-2 blockers (or α 2 blockers) are a subset of the alpha blocker class of drugs and are antagonists to the α 2 adrenergic receptor.They are mainly used in research, having found limited clinical application in human medicine.
Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha 2A, alpha 2B, and alpha 2C.These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.
11552 Ensembl ENSG00000274286 ENSMUSG00000058620 UniProt P18089 P30545 RefSeq (mRNA) NM_000682 NM_009633 RefSeq (protein) NP_000673 NP_033763 Location (UCSC) Chr 2: 96.11 – 96.12 Mb Chr 2: 127.21 – 127.21 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The alpha-2B adrenergic receptor (α 2B adrenoceptor), is a G-protein coupled receptor. It is a subtype of the adrenergic ...
The alpha-2A adrenergic receptor (α 2A adrenoceptor), also known as ADRA2A, is an α 2-adrenergic receptor, and also denotes the human gene encoding it. [5] Receptor
Clonidine, sold under the brand name Catapres among others, is an α 2A-adrenergic receptor agonist [12] medication used to treat high blood pressure, ADHD, drug withdrawal (e.g., alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. [13]