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The metanephrogenic blastema or metanephric blastema (or metanephric mesenchyme, or metanephric mesoderm) is one of the two embryological structures that give rise to the kidney, the other being the ureteric bud. The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.
Kidney stones – deviant orientation of kidneys combined with slow urine flow and kidney obstruction may increase the risk of developing kidney stones. Treatment is further complicated if patient possesses aberrant skeletal anatomy. [5] It is estimated 36% of patients with horseshoe kidneys will develop kidney stones. [6]
The ureteric bud, also known as the metanephric diverticulum, [1]: 50 is a protrusion from the mesonephric duct during the development of the urinary and reproductive organs. [ 2 ] [ 3 ] It later develops into a conduit for urine drainage from the kidneys, which, in contrast, originate from the metanephric blastema .
The glands may be the source of female ejaculation, [3] [4] [5] but this has not been proven. [4] Because they and the male prostate act similarly by secreting prostate-specific antigen (PSA), which is an ejaculate protein produced in males, and prostatic acid phosphatase, some authors refer to the Skene's glands as the "female prostate".
The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
The different colors indicate embryologic origin of structure: a) red = metanephric duct , b) yellow = urogenital sinus (bladder and urethra), c) blue = Wolffian duct (Gartner's ducts in female, seminal vesicles and vasa deferentia in male), pink = Müllerian ducts (vagina in female, prostatic utricle in male), green = hindgut . Specialty
The cause of acute kidney injury in most cases is ischemic or toxic injury. Mammalian kidneys are susceptible to ischemic injury because mammals lack a renal-portal system , and as a result, vascular vasoconstriction in the glomeruli can lead to decreased blood supply to the entire kidney.
It is not certain what causes this pain, but researchers have proposed that the small numerous stones seen in MSK may cause obstruction of the small tubules and collecting ducts in the kidney. This pain can be constant, can often be debilitating and treatment is challenging. Narcotic medication, even in large quantities, is sometimes not adequate.