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Epoetin beta , sold under the brand name Neorecormon among others, is a synthetic, recombinant [4] form of erythropoietin, a protein that promotes the production of red blood cells. It is an erythropoiesis-stimulating agent (ESA) that is used to treat anemia , commonly associated with chronic kidney failure and cancer chemotherapy .
The 2020 Cochrane Anaesthesia Review Group review of erythropoietin (EPO) plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non‐cardiac surgery [11] demonstrated that patients were much less likely to require red cell transfusion and in those transfused, the volumes were unchanged (mean ...
Macmillan Publishers (occasionally known as the Macmillan Group; formally Macmillan Publishers Ltd in the UK and Macmillan Publishing Group, LLC in the US) is a British publishing company traditionally considered to be one of the "Big Five" English language publishers (along with Penguin Random House, Hachette, HarperCollins and Simon & Schuster).
In 2007 Locsin co-edited the book Technology and Nursing: Practice, Concepts, and Issues, released by Palgrave-Macmillan Co., London, UK, In 2009, with Dr. Marguerite Purnell as co-editor, published, A Contemporary Nursing Process: The (Un)Bearable Weight of Knowing in Nursing by Springer Publishing Co.
In addition, erythropoietin is bound by circulating red blood cells; low circulating numbers lead to a relatively high level of unbound erythropoietin, which stimulates production in the bone marrow. Recent studies have also shown that the peptide hormone hepcidin may play a role in the regulation of hemoglobin production, and thus affect ...
Erythropoietin is used to treat people with anemia resulting from critical illness. In a randomized controlled trial, [14] erythropoietin was shown to not change the number of blood transfusions required by critically ill patients. A surprising finding in this study was a small mortality reduction in patients receiving erythropoietin.
Erythropoietin is a sialoglycoprotein hormone produced by peritubular cells of kidney. Granulocyte -macrophage colony-stimulating factor and granulocyte CSF are given to stimulate white blood cell formation in cancer patients who are receiving chemotherapy , which tends to kill their red bone marrow cells as well as the cancer cells.