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Glycosaminoglycans [1] (GAGs) or mucopolysaccharides [2] are long, linear polysaccharides consisting of repeating disaccharide units (i.e. two-sugar units). The repeating two-sugar unit consists of a uronic sugar and an amino sugar , except in the case of the sulfated glycosaminoglycan keratan , where, in place of the uronic sugar there is a ...
The components of the ground substance vary depending on the tissue. Ground substance is primarily composed of water and large organic molecules, such as glycosaminoglycans (GAGs), proteoglycans, and glycoproteins. GAGs are polysaccharides that trap water, giving the ground substance a gel-like texture.
Keratan sulfate (KS), also called keratosulfate, is any of several sulfated glycosaminoglycans (structural carbohydrates) that have been found especially in the cornea, cartilage, and bone. It is also synthesized in the central nervous system where it participates both in development [1] and in the glial scar formation following an injury. [2]
Mucopolysaccharidoses are a group of metabolic disorders caused by the absence or malfunctioning of lysosomal enzymes needed to break down molecules called glycosaminoglycans (GAGs). These long chains of sugar carbohydrates occur within the cells that help build bone, cartilage, tendons, corneas, skin and connective tissue.
Glycosaminoglycans (GAGs) are long unbranched polysaccharides consisting of a repeating disaccharide unit. The general disaccharide unit consists of an N-acetyl-hexosamine and a hexose or hexuronic acid, either or both of which may be sulfated.
A body was found in the passenger seat of a vehicle after a driver was pulled over during a traffic stop in Georgia on the night of Wednesday, Jan. 29, police say. According to a Feb. 3 news ...
Glycosaminoglycans (GAGs) Small proteoglycans Large proteoglycans chondroitin sulfate/dermatan sulfate: decorin, 36 kDa biglycan, 38 kDa aggrecan, 220 kDa, the major proteoglycan in cartilage: Heparan sulfate proteoglycan (HSPGs) heparan sulfate/chondroitin sulfate: testican, 44 kDa perlecan, 400–470 kDa betaglycan, >300 kDa agrin, >500 kDa
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