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In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. [1] It is a fixed dose combination of isoniazid and rifampicin (rifampin). [1] It is used together with other antituberculosis medication. [1] It is taken by mouth. [1] It is on the World Health Organization's List of Essential Medicines. [2]
Rifampin rapidly kills fast-dividing bacilli strains as well as "persisters" cells, which remain biologically inactive for long periods of time that allow them to evade antibiotic activity. [7] In addition, rifabutin and rifapentine have both been used against tuberculosis acquired in HIV-positive patients.
Terapia S.A. is a Romanian pharmaceutical company founded in 1921. [1] The company is headquartered in Cluj-Napoca, Cluj, Romania and has regional centers in Moscow City, Russian Federation and Kyiv, Ukraine.
As of January 2021, the FDA continues to investigate the presence of 1-methyl-4-nitrosopiperazine (MNP) in rifampin or 1-cyclopentyl-4-nitrosopiperazine (CPNP) in rifapentine approved for sale in the US. [12]
Vietnam National Children's Hospital (VNCH) is a medical facility in Hanoi.Initially established in 1969 as Institute for the Protection of Children's Health. It was also known as Vietnam-Sweden Children’s Hospital, Olof Palme Pediatric Institute, and National Hospital of Pediatrics (NHP) before adopting its present name in 2016.
The pharmaceutical industry in Romania is prosperous, with an average revenue of 8.3 billion lei per year. [1] Value chain in the pharmaceutical industry has increased significantly in the last decade in all segments, contributing with over 1% to GDP (2010). [2] There are 22 plants of productions which receive subsidies from the state. [3]
Antibiotice Iași is a public pharmaceutical company which is one of the largest drug producing company in Romania. It is 53.02%-owned by the Romanian Ministry of Health . [ 3 ] Its research center and production facilities are based in Valea Lupului , a commune near Iași .