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Dermatitis herpetiformis (DH) is a chronic autoimmune blistering skin condition, [3] characterised by intensely itchy blisters filled with a watery fluid. [4] DH is a cutaneous manifestation of coeliac disease, [5] although the exact causal mechanism is not known.
The classic symptoms of untreated coeliac disease include diarrhea, steatorrhoea, iron-deficiency anemia, and weight loss or failure to gain weight. Other common symptoms may be subtle or primarily occur in organs other than the bowel itself. [34] It is also possible to have coeliac disease without any of the classic symptoms at all. [18]
A four-of-five rule was proposed 2010 for confirming celiac disease, with the disease confirmed if at least four of the following five criteria are satisfied: [2] [68] typical symptoms of celiac disease; positivity of serum celiac disease immunoglobulin, A class autoantibodies at high titer; human leukocyte antigen (HLA)-DQ2 or DQ8 genotypes;
There’s also the potential that people with celiac disease may be sensitive to the avenin protein in colloidal oatmeal, and it could cause a rash or an itch for these individuals, Dr. Holman says.
Getting diagnosed can take years and symptoms can mimic other ailments, but celiac is a serious autoimmune disease that can lead to heart disease, bowel cancer and potential infertility in women.
This condition is known as refractory coeliac disease (RCD), defined as malabsorption due to gluten-related enteropathy (villous atrophy or elevated intraepitheal lymphocytes) after initial or subsequent failure of a strict gluten-free diet (usually 1 year) and after exclusion of any disorder mimicking coeliac disease.
For individuals with gluten sensitivity or celiac disease, gluten can trigger an immune response, leading to more inflammation and potentially worsening autoimmune conditions like alopecia areata ...
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...