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Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia . Probenecid was developed as an alternative to caronamide [ 1 ] to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and ...
In the early 20th century, decades before the first chemical antibiotics were developed, Dr. Niels Finsen discovered that blue light could be used to treat skin infections. [6] In the following years, Finsen's phototherapy was used in many European medical institutions as a topical antimicrobial. [7]
Specimens are collected from affected body sites, preferably before antibiotics are given. For example, a person in an intensive care unit may develop a hospital-acquired pneumonia . There is a chance the causal bacteria, or its sensitivity to antibiotics, may be different to community-acquired pneumonia . [ 2 ]
Sulopenem/probenecid, sold under the brand name Orlynvah, is a fixed-dose combination medication used for the treatment of urinary tract infections. [1] It contains sulopenem , a penem antibacterial , as the prodrug sulopenem etzadroxil; and probenecid , a renal tubular transport inhibitor .
Therefore, an antibiotic with PAE would require less frequent administration and it could improve patient adherence with regard to pharmacotherapy. [ 3 ] [ 5 ] Proposed mechanisms include (1) slow recovery after reversible nonlethal damage to cell structures; (2) persistence of the drug at a binding site or within the periplasmic space ; and (3 ...
This treatment effectively cured his gastritis and eliminated the H. pylori infection. This is not the current eradication protocol. [citation needed] One of the first "modern" eradication protocols was a one-week triple therapy, which the Sydney gastroenterologist Thomas Borody formulated in 1987. [14]
One or both ingredients may be antibiotics. [1] Antibiotic combinations are increasingly important because of antimicrobial resistance. [2] This means that individual antibiotics that used to be effective are no longer effective, [1] and because of the absence of new classes of antibiotic, they allow old antibiotics to be continue to be used. [2]
Outpatient parenteral antibiotic therapy (OPAT) is used to administer non-oral antibiotics (usually intravenously) without the need for ongoing hospitalisation. OPAT is particularly useful for people who are not severely ill but do require a prolonged course of treatment that cannot be given in oral form. [ 1 ]