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The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [ 5 ] [ 65 ] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke , and 5 cases of muscle damage per 10,000 people treated. [ 34 ]
The Kobayashi red yeast rice scandal (Japanese: 小林製薬紅麹サプリメント問題) is an ongoing widespread supplement contamination that was first noted on 22 March 2024, resulting in numerous health problems to people taking the supplements in Japan and Taiwan. Up to 80 people died after taking the supplements, with at least 500 more ...
SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
The Osaka-based drugmaker said it was investigating a suspected link between the products and their effects on the kidney. Beni koji contains Monascus purpureus, a red mould that is also used as a ...
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[citation needed] Annual cost to the UK National Health Service (NHS) in 2018, for 5–40 mg rosuvastatin daily (of one person) was £24-40, compared to £10-20 for 20–80 mg simvastatin. [ 38 ] In 2013, it was the fourth-highest-selling drug in the United States, accounting for approximately $5.2 billion in sales. [ 39 ]