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Various UV-emitting devices can be used for SARS-CoV-2 disinfection, and these devices may help in reducing the spread of infection. [102] SARS-CoV-2 can be inactivated by a wide range of UVC wavelengths, and the wavelength of 222 nm provides the most effective disinfection performance. [102] Disinfection is a function of UV intensity and time.
Nucleic acids play important roles as cellular information storage and gene regulation machinery. In efforts to regulate this machinery by light, DNA and RNA have been modified with photocleavable groups at the backbone (in an approach called ‘statistical backbone caging’; the protection groups react mainly with backbone phosphate groups).
A germicidal lamp (also known as disinfection lamp or sterilizer lamp) is an electric light that produces ultraviolet C (UVC) light. This short-wave ultraviolet light disrupts DNA base pairing , causing formation of pyrimidine dimers , and leads to the inactivation of bacteria , viruses , and protozoans .
Photoactivated peptides have shown potential for various applications, including cancer therapy, other light-controlled drugs, and as tools to probe molecular interactions in intact cells and whole organisms. [8] Initial studies demonstrated that these peptides could effectively kill B-cell lymphoma cancer cells.
This is a list of instruments used in microbiological sterilization and disinfection. [1] [2] [3] Instrument list.
Photodynamic skin disinfection is effective at killing topical microbes, including drug-resistant bacteria, viruses, and fungi. [ 43 ] [ better source needed ] Photodynamic disinfection remains effective after repeat treatments, with no evidence of resistance formation. [ 44 ]
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