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Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
At steady state, the systemic exposure for armodafinil is 1.8 times the exposure observed after a single dose. The concentration-time profiles of the (R)-(−)-enantiomer following a single dose of 50 mg Nuvigil or 100 mg Provigil (modafinil being a 1:1 mixture of (R)-(−)- and (S)-(−)- enantiomers
[3] [2] [4] The modafinil analogues are of interest in the potential treatment of a condition involving the misuse of stimulant drugs (psychostimulant use disorder or PSUD), as drugs that help increase motivation (pro-motivational agents) to treat motivational disorders, [4] [5] [6] and for treatment of neurodegenerative diseases such as ...
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Marte, who was busted on a drug conviction in 2009 that landed him a seven-year prison sentence, now projects his booming business will bring in $12 million this year, boasting an $800,000 monthly ...
The price or street value of cannabis varies widely depending on geographic area and potency. [288] Prices and overall markets have also varied considerably over time. In 1997, cannabis was estimated to be overall the number four value crop in the US, and number one or two in many states, including California, New York, and Florida.
Price of Weed (or priceofweed.com) is a user-generated database of marijuana prices. Users may submit prices and quantities for transactions, and their location is geolocated in order to generate a price index for states and cities. While user-generated prices have no inherent check on accuracy, the criminal status of marijuana in many ...
The clinic also spent nearly $100,000 during that period on Provigil, a stimulant that is “55 times more expensive than the generic equivalent,” the report said.