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Ecthyma gangrenosum is a type of skin lesion characterized by vesicles or blisters which rapidly evolve into pustules and necrotic ulcers with undermined tender erythematous border. " Ecthyma " means a pus forming infection of the skin with an ulcer, "gangrenosum" refers to the accompanying gangrene or necrosis.
Diagnosis is by biopsy and analysis of any skin lesion that has signs of being potentially cancerous. [1] Avoiding UV light and using sunscreen in UV-bright sun conditions may prevent melanoma. [2] Treatment typically is removal by surgery of the melanoma and the potentially affected adjacent tissue bordering the melanoma. [1]
• Changing skin lesions (in terms of color, size, shape, or texture) or symptomatic skin lesions (those that are painful, itchy, scabbing, ulcerated, prone to bleeding, or non-healing)
The lesions are usually as described above, but may occasionally be plaque-like (often on the soles of the feet) or even involved in skin breakdown with resulting fungating lesions. Associated swelling may be from either local inflammation or lymphoedema (obstruction of local lymphatic vessels by the lesion).
Areas of the skin exposed to friction and radiation are typically affected first. [1] Over time affected skin may become darker, stiffen, peel, or bleed. [1] [3] There are two main types of pellagra, primary and secondary. [1] Primary pellagra is due to a diet that does not contain enough niacin and tryptophan. [1]
Lupus vulgaris (also known as tuberculosis luposa [1]) are painful cutaneous tuberculosis skin lesions with nodular appearance, most often on the face around the nose, eyelids, lips, cheeks, ears [2] and neck. It is the most common Mycobacterium tuberculosis skin infection. [3] The lesions may ultimately develop into disfiguring skin ulcers if ...
Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [ 1 ] Basal cells in the basal layer ( stratum basale ) of the skin are sometimes referred to as basal keratinocytes . [ 2 ]
Diagnosis is based on a skin biopsy and involvement of more than 30% of the skin. [3] TEN is a type of severe cutaneous adverse reactions (SCARs), together with SJS, a SJS/TEN, and drug reaction with eosinophilia and systemic symptoms. [5] It is called SJS when less than 10% of the skin is involved and an intermediate form with 10 to 30% ...