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Many Ebola vaccine candidates had been developed in the decade before 2014, but none has yet been approved for clinical use in humans. [211] Several promising vaccine candidates have been shown to protect nonhuman primates (usually macaques) against lethal infection, and some are now going through the clinical trial process. [212] [213]
The Ervebo vaccine, developed by Merck, is a single-dose vaccine. It works by using a modified virus to produce antibodies against Ebola, equipping the immune system to recognise and neutralise ...
A number of companies were expected to develop Ebola vaccines: GlaxoSmithKline, NewLink Genetics, Johnson & Johnson, and Bavarian Nordic. [82] Another company, Emergent BioSolutions, was a contestant for manufacturing new doses of ZMapp, [citation needed] a drug for Ebola virus disease treatment originally developed by Mapp Biopharmaceutical. [83]
In April 2019, following a large-scale ring-vaccination scheme in the DRC outbreak, the WHO published the preliminary results of its research, in association with the DRC's Institut National pour la Recherche Biomedicale, into the effectiveness of the ring vaccination program, stating that the rVSV-ZEBOV-GP vaccine had been 97.5% effective at stopping Ebola transmission, relative to no ...
A stockpile of half-a-million Ebola vaccine doses was established by Gavi and other global health partners in 2019 for use in outbreaks of haemorrhagic fever, which has an average fatality rate of ...
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Researcher working with the Ebola virus while wearing a BSL-4 positive pressure suit. There is a cure for the Ebola virus disease that is currently approved for market the US government has inventory in the Strategic National Stockpile. [1] For past and current Ebola epidemics, treatment has been primarily supportive in nature. [2]
Orthoebolavirus zairense [1] or Zaire ebolavirus, more commonly known as Ebola virus (/ i ˈ b oʊ l ə, ɪ-/; EBOV), is one of six known species within the genus Ebolavirus. [2] Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD).