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The World Health Organization (WHO) does not recommend the use of combined oral contraceptive pills in women with breast cancer. [41] [97] Since combined oral contraceptive pills contain both estrogen and progestin, they are not recommended to be used in those with hormonally-sensitive cancers, including some types of breast cancer.
Between 2015 and 2017, 64.9% of women ages 15–49 in the United States were using contraception, and of those 12.6% were using the oral contraceptive pill. [46] There are approximately 100 million users of combined oral contraceptives worldwide, with use being more common in Western Europe, Northern Europe, and the United States. [47]
As of June 2018, it is in phase II clinical trials for breast cancer and prostate cancer. [citation needed] In addition to a single-drug formulation, estetrol is being developed in combination with the progestin drospirenone for hormonal contraception (use as a birth control pill) to prevent pregnancy.
Breast cancer is the UK’s most common type of cancer, with approximately 56,000 new cases each year. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 ...
Progesterone was studied in the treatment of breast cancer in 1951 and 1952, but with relatively modest results. [158] [159] [160] Megestrol acetate was first studied in the treatment of breast cancer in 1967, and was one of the first progestins to be evaluated for the treatment of this disease. [6] [30] [161] A second study was conducted in 1974.
Estradiol-containing birth control pills were initially studied in the 1970s, with the first report published in 1977. [230] [231] Development of birth control pills containing estradiol was motivated by the thrombotic risks of ethinylestradiol that were uncovered in the 1960s and 1970s.
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