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Exposure to bacterial endotoxin in early childhood may prevent the development of asthma, but exposure at an older age may provoke bronchoconstriction. [70] Evidence supporting the hygiene hypothesis includes lower rates of asthma on farms and in households with pets. [69] Use of antibiotics in early life has been linked to the development of ...
An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies ...
[8] [9] The suggestion is that for a child being exposed to microbes early in life, taking fewer antibiotics, living in a large family, and growing up in the country stimulate the T H 1 response and reduce the odds of developing asthma. [10] Asthma is associated with a procoagulant state in the bronchoalveolar space. [11]
In 1986, some European countries banned the use of antibiotics because of research they found that linked antibiotic use in livestock and drug resistant bacteria in humans. [11] The European Union regulated in 2006 against antibiotics for growth promotion purposes. [12] It was estimated in 2014 that over 80% of the world's antibiotic use was on ...
Common forms of antibiotic misuse include excessive use of prophylactic antibiotics in travelers and failure of medical professionals to prescribe the correct dosage of antibiotics on the basis of the patient's weight and history of prior use. Other forms of misuse include failure to take the entire prescribed course of the antibiotic ...
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
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In patients with long QT syndrome, cardiac disease, or patients taking other QT-prolonging medications, this can increase risk for life-threatening arrhythmias. [ 15 ] In one trial, the use of short-term clarithromycin treatment was correlated with an increased incidence of deaths classified as sudden cardiac deaths in stable coronary heart ...