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A rapid increase of studies in schizophrenia has covered topics such as abnormal activity in "motor tasks, working memory attention, word fluency, emotion processing, and decision making." [ 8 ] Researchers also focus on identifying biomarkers through fMRI scans that could aid early diagnosis.
Working memory is a cognitive system with a limited capacity that can hold information temporarily. [1] ... Using spatial memory tests and fMRI scans, ...
Prolonged match-to-sample working memory task: Left dorsolateral prefrontal cortex: Increased GABA level during the first working memory run and continuously decreased during subsequent three runs. Decrease of GABA over time correlated with decreases in reaction time and higher task accuracy. [47] Presentation of abstract and real world objects
Despite these difficulties, fMRI has been used clinically to map functional areas, check left-right hemispherical asymmetry in language and memory regions, check the neural correlates of a seizure, study how the brain recovers partially from a stroke, and test how well a drug or behavioral therapy works. Mapping of functional areas and ...
During a task assessing working memory—the short-term storage of information that can be applied to activities such as reasoning and problem-solving—the majority of recent (68%) and heavy ...
Functional connectivity analyses allow the characterization of interregional neural interactions during particular cognitive or motor tasks or merely from spontaneous activity during rest. FMRI and PET enable creation of functional connectivity maps of distinct spatial distributions of temporally correlated brain regions called functional networks.
In experiments with the macaque monkey, Earl Miller and his colleagues used the delayed matching to sample (DMS) task to assess working memory in monkeys. [33] The monkey was required to fixate on a computer screen while coloured images were displayed serially for 0.5 seconds, and separated by a one-second delay.
There is some evidence from an fMRI study that autistic individuals are more likely to use visual cues rather than verbal cues on some working memory tasks, based on the differentially high activation of right parietal regions over left parietal regions in an N-back working memory task with letters.