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Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
It is used as endocrine therapy for women with estrogen or progesterone receptor-positive, stage 4 or recurrent metastatic breast cancer [7] and has demonstrated similar efficacy compared to tamoxifen as adjuvant treatment of breast cancer and in the treatment of metastatic breast cancer. [6]
Observational studies of systemic HRT after breast cancer are generally reassuring. If HRT is necessary after breast cancer, estrogen-only therapy or estrogen therapy with a progestogen may be safer options than combined systemic therapy. [71] In women who are BRCA1 or BRCA2 mutation carriers, HRT does not appear to impact breast cancer risk. [72]
Treatment for breast cancer triggered painful vaginal symptoms, but I was too embarrassed to talk to my doctor about it. Here's how I improved my sex life. Breast Cancer Threw Me Into Menopause at ...
[1] [47] HDE was the first medical therapy for prostate cancer and breast cancer. [48] Pseudopregnancy was developed in the 1950s following the introduction of progestins with improved potency and pharmacokinetics , at which time it was used to treat hypoplasia of the uterus and breasts and endometriosis.
If we compare the two different dosage forms having same active ingredients and compare the two drug bioavailability is called comparative bioavailability. [18] Although knowing the true extent of systemic absorption (referred to as absolute bioavailability) is clearly useful, in practice it is not determined as frequently as one may think.
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