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The outline of the classical Hi-C workflow is as follows: cells are cross-linked with formaldehyde; chromatin is digested with a restriction enzyme that generates a 5’ overhang; the 5’ overhang is filled with biotinylated bases and the resulting blunt-ended DNA is ligated. [1]
Hydrochloric acid, also known as muriatic acid or spirits of salt, is an aqueous solution of hydrogen chloride (HCl). It is a colorless solution with a distinctive pungent smell.
Human–computer interaction (HCI) is research in the design and the use of computer technology, which focuses on the interfaces between people and computers. HCI researchers observe the ways humans interact with computers and design technologies that allow humans to interact with computers in novel ways.
Human–computer information retrieval (HCIR) is the study and engineering of information retrieval techniques that bring human intelligence into the search process. It combines the fields of human-computer interaction (HCI) and information retrieval (IR) and creates systems that improve search by taking into account the human context, or through a multi-step search process that provides the ...
A canaliculus is an adaptation found on gastric parietal cells. It is a deep infolding, or little channel, which serves to increase the surface area, e.g. for secretion. The parietal cell membrane is dynamic; the numbers of canaliculi rise and fall according to secretory n
“High-content” or visual biology technology has two purposes, first to acquire spatially or temporally resolved information on an event and second to automatically quantify it. Spatially resolved instruments are typically automated microscopes , and temporal resolution still requires some form of fluorescence measurement in most cases.
The Human–Computer Interaction Institute (HCII) is a department within the School of Computer Science at Carnegie Mellon University (CMU) in Pittsburgh, Pennsylvania.It is considered one of the leading centers of human–computer interaction research, [1] and was named one of the top ten most innovative schools in information technology by Computer World in 2008. [2]
Natural computing, [1] [2] also called natural computation, is a terminology introduced to encompass three classes of methods: 1) those that take inspiration from nature for the development of novel problem-solving techniques; 2) those that are based on the use of computers to synthesize natural phenomena; and 3) those that employ natural materials (e.g., molecules) to compute.