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V = 70 kg × 0.6 L of water/kg of body mass = 42 L = 42,000 mL; Therefore: Kt/V = 1.23. This means that if you dialyze a patient to a Kt/V of 1.23, and measure the postdialysis and predialysis urea nitrogen levels in the blood, then calculate the URR, then −ln(1−URR) should be about 1.23.
Kt/V, like the URR, focuses on urea as the target solute, and is based on the assumption that removal of urea is from a single space – urea distribution volume, or similar in capacity to the total body water. The urea distribution volume , although traditionally thought of as 60% of body weight, may actually be closer to 50% of the body ...
It is complex and tedious to calculate, although web-based calculators are available to do this fairly easily. Many nephrologists have difficulty understanding it. Urea is not associated with toxicity. [4] Standardized Kt/V only models the clearance of urea and thus implicitly assumes the clearance of urea is comparable to other toxins.
Creatinine is the product of muscle creatine catabolism. Both are relatively small molecules (60 and 113 daltons, respectively) that distribute throughout total body water. In Europe, the whole urea molecule is assayed, whereas in the United States only the nitrogen component of urea (the blood or serum urea nitrogen, i.e., BUN or SUN) is measured.
Selective catalytic reduction (SCR) means converting nitrogen oxides, also referred to as NO x with the aid of a catalyst into diatomic nitrogen (N 2), and water (H 2 O). A reductant, typically anhydrous ammonia (NH 3), aqueous ammonia (NH 4 OH), or a urea (CO(NH 2) 2) solution, is added to a stream of flue or exhaust gas and is reacted onto a ...
Phenol in the Berthelot reagent can be replaced by a variety of phenolic reagents, the most common being sodium salicylate, which is significantly less toxic. [1] This has been used for blood urea nitrogen (BUN) determinations and commonly is used to determine water and soil total and ammonia-N. Replacement of phenol by 2-phenylphenol reduces interferences by a variety of soil and water ...
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