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A model called the "reverse Warburg effect" describes cells releasing energy by glycolysis, but which are not tumor cells, but stromal fibroblasts. [32] In this scenario, the stroma become corrupted by cancer cells and turn into factories for the synthesis of energy rich nutrients.
Scientist Otto Warburg, whose research activities led to the formulation of the Warburg hypothesis for explaining the root cause of cancer.. The Warburg hypothesis (/ ˈ v ɑːr b ʊər ɡ /), sometimes known as the Warburg theory of cancer, postulates that the driver of carcinogenesis (cancer formation) is insufficient cellular respiration caused by insult (damage) to mitochondria. [1]
The inversion to the Warburg effect is a corollary to the Warburg hypothesis or Warburg effect that was discovered in obesity. Warburg's hypothesis suggests that tumor cells proliferate quickly and aggressively by obtaining energy or ATP, through high glucose consumption and lactate production. [1]
People with psychotic depression experience the symptoms of a major depressive episode, along with one or more psychotic symptoms, including delusions and/or hallucinations. [2] Delusions can be classified as mood congruent or incongruent, depending on whether or not the nature of the delusions is in keeping with the individual's mood state. [2]
Substance-induced psychosis (commonly known as toxic psychosis or drug-induced psychosis) is a form of psychosis that is attributed to substance intoxication, withdrawal or recent consumption of psychoactive drugs. It is a psychosis that results from the effects of various substances, such as medicinal and nonmedicinal substances, legal and ...
Brief psychotic disorder—according to the classifications of mental disorders DSM-IV-TR and DSM-5—is a psychotic condition involving the sudden onset of at least one psychotic symptom (such as disorganized thought/speech, delusions, hallucinations, or grossly disorganized or catatonic behavior) lasting 1 day to 1 month, often accompanied by emotional turmoil.
Paraphrenia is often associated with a physical change in the brain, such as a tumor, stroke, ventricular enlargement, or neurodegenerative process. [4] Research that reviewed the relationship between organic brain lesions and the development of delusions suggested that "brain lesions which lead to subcortical dysfunction could produce delusions when elaborated by an intact cortex".
Folie à deux (French for 'madness of two'), [1] also called shared psychosis [3] or shared delusional disorder (SDD), is a rare psychiatric syndrome in which symptoms of a delusional belief [4] are "transmitted" from one individual to another.