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Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
[1] [13] [2] It has also been used off-label for certain other indications, like treatment of low blood pressure. [14] [15] [16] At higher doses, it may produce various additional effects including stimulant, [17] [1] appetite suppressant, [18] and performance-enhancing effects. [19] [20] In relation to this, non-medical use of pseudoephedrine ...
The concern goes beyond ineffectiveness; phenylephrine can come with side effects such as headaches, insomnia and nervousness. At higher doses, it can increase blood pressure.
Last year alone, oral decongestants with phenylephrine in the U.S. generated almost $1.8 billion in sales, FDA data shows. Currently, phenylephrine is considered safe, but without effectiveness ...
Side effects of etilefrine include nausea, tremors, and palpitations, among others. [5] Etilefrine is an agonist of the α-and β-adrenergic receptors. [6] It is a substituted phenethylamine and is related to epinephrine, phenylephrine, and norfenefrine. [2] Etilefrine was first described and introduced for medical use by 1949. [7] [8]
As Yahoo Life reported last year, when taken in oral form, phenylephrine is metabolized so quickly that the amount absorbed into the bloodstream ends up being less than 1% of what was originally ...
First-line treatment; Intravenous administration [10] Belladonna alkaloid; Side effects include urinary retention, dry mouth, blurred vision; Glycopyrrolate: Quaternary ammonium compound; Does not cross blood-brain barrier; Hyperhidrosis. Reduce rate of sweating by blocking parasympathetic receptors in the central nervous system, smooth muscle ...
Patients with NOH have depleted levels of norepinephrine which leads to decreased blood pressure or hypotension upon orthostatic challenge. [14] Droxidopa works by increasing the levels of norepinephrine in the peripheral nervous system (PNS), thus enabling the body to maintain blood flow upon and while standing .