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There are efforts to define core sets of patient-relevant outcome variables to be measured in clinical trials in general [28] and for multi-modal pain therapy. [29] Meanwhile, a core outcome measure set based on PROMS was developed with routine data and validated for operationalizing success in multimodal pain therapy. [30]
The Patient-Reported Outcomes Measurement Information System [1] (PROMIS) provides clinicians and researchers access to reliable, valid, and flexible measures of health status that assess physical, mental, and social well–being from the patient perspective. PROMIS measures are standardized, allowing for assessment of many patient-reported ...
An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment. [1] [2] Measures can often be quantified using effect sizes. [3]
Outcome measurement is therefore an important but neglected tool in improving quality of healthcare provision. It has been argued that it is vital that the patient has been meaningfully involved in decisions about whether or not to embark on an intervention (e.g. a test, an operation, a medicine).
Outcome measurement is a matter of representing the circumstances defined as the outcome by means of observable indicators that vary systematically with changes or differences in those circumstances. [8] Outcome measurement is a systematic way to assess the extent to which a program has achieved its intended outcomes. [18]
The Institute for Work & Health (IWH) is an independent, not-for-profit research organization based in Toronto, Canada.Its mission is to “promote, protect and improve the safety and health of working people by conducting actionable research that is valued by employers, workers, and policy-makers.” [1]
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It is not always necessary to validate an ePRO measure against a pre-existing paper version. In some cases, an instrument may be developed and validated from the beginning in electronic form. More commonly, perhaps, new instruments will be developed in parallel for paper and electronic use, as is the case with the PROMIS (Patient-Reported ...