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Hypericum perforatum, commonly known as St John's wort (sometimes perforate St John's wort or common St John's wort), is a flowering plant in the family Hypericaceae.It is a perennial plant that grows up to 1 metre (3 ft 3 in) tall, with many yellow flowers that have clearly visible black glands around their edges, long stamens (male reproductive organs), and three pistils (female reproductive ...
Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). [2] Hyperforin may be involved in the pharmacological effects of St. John's wort, [2] specifically in its antidepressant effects. [3] [4] [5]
St John's wort: Tipton's weed, Klamath weed Hypericum perforatum: Photosensitization, [3] [15] GI disturbances, "allergic reactions, fatigue, dizziness, confusion, dry mouth" [15] Valerian: garden valerian, garden heliotrope, all-heal Valeriana officinalis "drowsiness, GI upset, headache, palpitations, insomnia", [3] oversedation ...
It can be caused by certain drug interactions, as well as drinking alcohol while taking a medication like Lexapro. ... Over-the-counter treatments for depression such as St. John’s wort. NSAIDs ...
The most commonly implicated conventional drugs in herb-drug interactions are warfarin, insulin, aspirin, digoxin, and ticlopidine, due to their narrow therapeutic indices. [21] [22] The most commonly implicated herbs involved in such interactions are those containing St. John’s Wort, magnesium, calcium, iron, or ginkgo. [21]
The beetles Chrysolina quadrigemina, Chrysolina hyperici and the St. John's-wort root borer (Agrilus hyperici) feed on common St. John's-wort (H. perforatum) plants and have been used for biocontrol where the plant has become an invasive weed. [13] Hypericum species are the only known food plants of the caterpillar of the treble-bar, a species ...
The more alcohol and alprazolam taken, the worse the interaction. [38] Combination of alprazolam with the herb kava can result in the development of a semi-comatose state. [57] Plants in the genus Hypericum, including St. John's wort, conversely can lower the plasma levels of alprazolam and reduce its therapeutic effect. [58] [59] [60]
St. John's wort; Yohimbe; Tricyclic antidepressants (TCAs) Serotonin-norepinephrine reuptake inhibitors (SNRIs) Buspirone; Triptan; Mirtazapine; Methylene blue; Painkillers of the NSAIDs drug family may interfere and reduce efficiency of SSRIs and may compound the increased risk of gastrointestinal bleeds caused by SSRI use. [101] [103] [165 ...