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  2. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    For example, problems with both your privates and your heart can be associated with a vascular condition that affects blood flow. PDE5 inhibitors like sildenafil may not be safe for people who ...

  3. Can You Take Viagra With High Blood Pressure? - AOL

    www.aol.com/viagra-high-blood-pressure-115800298...

    When you have high blood pressure, your heart and blood vessels have to work harder to make blood flow through your body. This is pretty much the opposite of what sildenafil does — as a reminder ...

  4. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    When that happens, blood pressure in the lungs increases, and the heart has to work harder to get blood through those tiny arteries — a process that can eventually tire out the lungs ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil acts by blocking phosphodiesterase 5 (PDE 5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [8] It requires sexual arousal to work, and does not by itself cause or increase sexual arousal. [8] It also results in dilation of the blood vessels in the lungs. [8]

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    Since it was originally used as a treatment for pulmonary hypertension (a form of high blood pressure in the lungs) and functions as a vasodilator that increases blood flow to the lungs ...

  8. Chronotropic - Wikipedia

    en.wikipedia.org/wiki/Chronotropic

    Chronotropic effects (from chrono-, meaning time, and tropos, "a turn") are those that change the heart rate. Chronotropic drugs may change the heart rate and rhythm by affecting the electrical conduction system of the heart and the nerves that influence it , such as by changing the rhythm produced by the sinoatrial node .

  9. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    A mental health professional can help you with these issues. You might not feel attracted or in the mood for intimacy. Viagra works by improving blood flow to your privates, not by changing your mood.