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For example, problems with both your privates and your heart can be associated with a vascular condition that affects blood flow. PDE5 inhibitors like sildenafil may not be safe for people who ...
When you have high blood pressure, your heart and blood vessels have to work harder to make blood flow through your body. This is pretty much the opposite of what sildenafil does — as a reminder ...
Since it was originally used as a treatment for pulmonary hypertension (a form of high blood pressure in the lungs) and functions as a vasodilator that increases blood flow to the lungs ...
Sildenafil acts by blocking phosphodiesterase 5 (PDE 5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [8] It requires sexual arousal to work, and does not by itself cause or increase sexual arousal. [8] It also results in dilation of the blood vessels in the lungs. [8]
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
When that happens, blood pressure in the lungs increases, and the heart has to work harder to get blood through those tiny arteries — a process that can eventually tire out the lungs ...
Sildenafil and other PDE-5 inhibitor medications can interact with other drugs, including several common medications used to treat chest pain, high blood pressure (sildenafil can cause low blood ...
Low blood pressure. Abnormal vision. ... attacks — a topic we’ve covered more in our guide to whether Viagra can cause a heart ... alcohol both affect blood flow throughout your body, but in ...