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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone has been studied at extremely high oral doses of up to 2,400 mg per day in clinical trials. [107] [168] Its oral median lethal dose (LD 50) is more than 1,000 mg/kg in mice, rats, and rabbits. [8] There is no specific antidote for overdose of spironolactone. [8]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    [61] [62] In addition, other studies have found that 100 mg/day spironolactone is significantly or near-significantly inferior to 500 mg/day flutamide in improving symptoms of acne and hirsutism. [ 63 ] [ 64 ] [ 65 ] One study compared placebo and dosages of spironolactone of 50, 100, 150, and 200 mg/day in the treatment of acne in women and ...

  4. Template:Pharmacokinetics of 100 mg per day spironolactone ...

    en.wikipedia.org/wiki/Template:Pharmacokinetics...

    Pharmacokinetics of 100 mg/day spironolactone and its metabolites Compound C max Tooltip Peak concentrations (day 1) C max Tooltip Peak concentrations (day 15) AUC Tooltip Area-under-the-curve concentrations (day 15) t 1/2 Tooltip Elimination half-life; Spironolactone: 72 ng/mL (173 nmol/L) 80 ng/mL (192 nmol/L) 231 ng•hour/mL (555 nmol ...

  5. Can Stress Actually Cause Female Hair Loss? - AOL

    www.aol.com/lifestyle/stress-actually-cause...

    Shedding more than 100 hairs a day (typically losing 50-100 is common) ... Spironolactone. Studies have shown that this once-daily pill can help treat female hair loss and promote new hair growth ...

  6. Everything You Need to Know About Acne, from Causes to ... - AOL

    www.aol.com/everything-know-acne-causes...

    Spironolactone: Spironolactone is used to treat high blood pressure but is also prescribed off-label for treating acne in women. Spironolactone reduces the amount of androgen hormones in your body ...

  7. Feminizing hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Feminizing_hormone_therapy

    4–6 mg/day Spironolactone: Aldactone: Antiandrogen: Oral: 100–400 mg/day ... the rate in the general population has been found to be 1.0–1.8 per 1000 person ...

  8. Androgenetic Alopecia: Everything to Know About Male ... - AOL

    www.aol.com/androgenetic-alopecia-everything...

    It’s normal to shed between 50 and 100 hairs per day. These hairs fall out as a natural result of your hair growth process, during which your hair grows to its normal length, rests and ...

  9. Canrenone - Wikipedia

    en.wikipedia.org/wiki/Canrenone

    Canrenone is an active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is considered to be partially responsible for their effects. [9] It has been found to have approximately 10 to 25% of the potassium-sparing diuretic effect of spironolactone, [ 16 ] whereas another metabolite, 7α-thiomethylspironolactone (7α-TMS ...