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Losartan should not be taken by people who are diabetic and taking aliskiren. [3] Anemia may occur, due to inhibition of the renin–angiotensin system. [ 17 ] As with other angiotensin receptor blockers, losartan may injure the liver, although this effect appears to be rare. [ 18 ]
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Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [1] [2] It consists of losartan, an angiotensin II receptor blocker; and hydrochlorothiazide, a thiazide diuretic. [1] [2] It is taken by mouth. [1] [2]
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The fundamental goal of treatment should be the prevention of the important endpoints of hypertension, such as heart attack, stroke and heart failure. Patient age, associated clinical conditions and end-organ damage also play a part in determining dosage and type of medication administered. [ 3 ]
However, they also recommend that patients should not stop taking aliskiren without talking to a healthcare professional. [50] Aliskiren in combination with hydrochlorothiazide was approved by the FDA in 2008 under the tradename Tekturna HCT. [51] [52]
Local news is usually coupled with a half-hour network newscast and possibly a syndicated news program. Unlike morning news shows, these are more generally targeted programs and feature more hard news stories (network evening newscasts, unlike their local counterparts, tend to limit weather and sports coverage unless it is a notable news story).
This is a listing of American television network programs currently airing or have aired during evening. Evening news programming begins at 6:30pm, 5:30pm, or 3:30pm Eastern Time Zone/Pacific Time Zone, after network affiliates' late local news. On PBS, and cable television, news starts at 6:00 pm, earlier, or later ET/PT.