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Gottron's sign is a pathognomonic cutaneous manifestation associated with dermatomyositis (DM), which is an inflammatory disorder affecting the skin and muscles. [1] The primary lesion of dermatomyositis appears as a violaceous, macular erythema with a symmetric distribution, which may progress and become poikilodermatous (atrophic with telangiectasia and pigmentary changes) and indurated (as ...
Diagnosis is by biopsy and analysis of any skin lesion that has signs of being potentially cancerous. [1] Avoiding UV light and using sunscreen in UV-bright sun conditions may prevent melanoma. [2] Treatment typically is removal by surgery of the melanoma and the potentially affected adjacent tissue bordering the melanoma. [1]
With regard to morphology, the initial lesion that characterizes a condition is known as the "primary lesion", and identification of such a lesions is the most important aspect of the cutaneous examination. [30] Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions". [1]
A lentigo (/ l ɛ n ˈ t aɪ ɡ oʊ /) (plural lentigines, / l ɛ n ˈ t ɪ dʒ ɪ n iː z /) is a small pigmented spot on the skin with a clearly defined edge, surrounded by normal-appearing skin. It is a harmless (benign) hyperplasia of melanocytes which is linear in its spread.
It can be polygonal but is never rectangular or square. [6] It can appear with a stalk, be thread-like or look warty. [3] Ulceration, oozing, bleeding or thin blood vessels may be present in a papule. [6] It can be soft or firm and its surface may be rough or smooth. [2] Some have crusts or scales. [2]
Treatment is based on the sub-type, whether the condition is localized or widespread, and the person's immune function. [6] Localized skin lesions may be treated by surgery, injections of chemotherapy into the lesion, or radiation therapy. [6] Widespread disease may be treated with chemotherapy or biologic therapy.
The center may break open and form an ulcer. [6] This initial skin lesion typically heals after 3–6 months. After weeks to years, joints and bones may become painful, fatigue may develop, and new skin lesions may appear. [6] The skin of the palms of the hands and the soles of the feet may become thick and break open. The bones (especially ...
The term morbilliform refers to a rash that looks like measles. [ 1 ] [ 2 ] The rash consists of macular lesions that are red and usually 2–10 mm in diameter but may be confluent in places. [ 3 ] A morbilliform rash is a rose-red flat ( macular ) or slightly elevated ( maculopapular ) eruption, showing circular or elliptical lesions varying ...