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Lymph node metastasis is the spread of cancer cells into a lymph node.. Lymph node metastasis is different from malignant lymphoma.Lymphoma is a cancer of lymph node, rather than cancer in the lymph node, because lymphoma originates from the lymph node itself, instead of originating elsewhere (e.g., the breast or colon) and spreading to the lymph nodes.
No assessment of neck lymph nodes N0: No evidence of spread N1: Ipsilateral, Single lymph node, ≤ 3 cm in size N2a: cancer cells have metastasised to a single lymph node, ipsilateral to main tumor, > 3 cm but ≤ 6 cm in size N2b: Cancer cells have metastasised to multiple lymph nodes, ipsilateral to mail tumor, > 6 cm in size N2c
Head and neck cancer is a general term encompassing multiple cancers that can develop in the head and neck region. These include cancers of the mouth, tongue, gums and lips ( oral cancer ), voice box ( laryngeal ), throat ( nasopharyngeal , oropharyngeal , [ 1 ] hypopharyngeal ), salivary glands , nose and sinuses .
Lymphovascular invasion, especially in carcinomas, usually precedes spread to the lymph nodes that drain the tissue in which the tumour arose. Conversely, cancers with lymph node spread (known as a lymph node metastases), usually have lymphovascular invasion. Lymph node metastases usually precede secondary tumours, i.e. distant metastases.
Lymphadenopathy: The most common symptom of Hodgkin is the painless enlargement of one or more lymph nodes. [14] The nodes may also feel rubbery and swollen when examined. The nodes of the neck, armpits and groin (cervical and supraclavicular) are most frequently involved (80–90% of the time, on average). [14]
Metastatic lymph nodes tend to feel hard and may be fixed to underlying tissues and may or may not be tender. [7] Usually the lymph nodes that directly drain the area of the cancer are affected by the spread (e.g. Sometimes metastatic cervical lymph node is detected before the main cancer). In such cases, this discovery leads to a search for ...