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  2. Epinephrine (medication) - Wikipedia

    en.wikipedia.org/wiki/Epinephrine_(medication)

    When epinephrine is mixed with local anesthetics, such as bupivacaine or lidocaine, and used for local anesthesia or intrathecal injection, it prolongs the numbing effect and motor block effect of the anesthetic by up to an hour. [45] Epinephrine is frequently combined with local anesthetic and can cause panic attacks. [46]

  3. Local anesthetic - Wikipedia

    en.wikipedia.org/wiki/Local_anesthetic

    Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...

  4. Retrobulbar block - Wikipedia

    en.wikipedia.org/wiki/Retrobulbar_block

    Following a negative aspiration for blood, 2–4 mLs of local anesthetic solution is injected and the needle is withdrawn. 2% Lidocaine (Xylocaine) and 0.5% to 0.75% bupivicaine (Marcaine) are two commonly used agents. Epinephrine, commonly mixed in with local anesthetics for vasoconstriction, is not used in seeing eyes as this can cause a ...

  5. Dental anesthesia - Wikipedia

    en.wikipedia.org/wiki/Dental_anesthesia

    However its use in low dose with local anesthetic administration is warranted. The epinephrine causes vasoconstriction which in turn reduces systemic distribution of the anesthetic as well as prolongs its action in addition to decreasing bleeding at the operating site. Lidocaine 2% with 1:100,000 adrenaline is the local anesthetic of choice in ...

  6. Bupivacaine - Wikipedia

    en.wikipedia.org/wiki/Bupivacaine

    It is sometimes used in combination with epinephrine to prevent systemic absorption and extend the duration of action. The 0.75% (most concentrated) formulation is used in retrobulbar block. [13] It is the most commonly used local anesthetic in epidural anesthesia during labor, as well as in postoperative pain management. [14]

  7. Local anesthesia - Wikipedia

    en.wikipedia.org/wiki/Local_anesthesia

    The following terms are often used interchangeably: Local anesthesia, in a strict sense, is anesthesia of a small part of the body such as a tooth or an area of skin. Regional anesthesia is aimed at anesthetizing a larger part of the body such as a leg or arm. Conduction anesthesia encompasses a great variety of local and regional anesthetic ...

  8. Procaine - Wikipedia

    en.wikipedia.org/wiki/Procaine

    Aside from its use as a dental anesthetic, procaine is used less frequently today, since more effective (and hypoallergenic) alternatives such as lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, thus is often coadministered with epinephrine for the purpose of ...

  9. Vasoconstriction - Wikipedia

    en.wikipedia.org/wiki/Vasoconstriction

    Vasoconstrictors are also used clinically to increase blood pressure or to reduce local blood flow. Vasoconstrictors mixed with local anesthetics are used to increase the duration of local anesthesia by constricting the blood vessels, thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage. [4] [5]