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Given its ability to capture a wide array of cellular responses, the Cell Painting assay has become a powerful tool in the field of drug discovery. [9] By comparing the morphological profiles of cells treated with different compounds, researchers can identify potential drug candidates, toxicity [10] or understand the mechanism of action of existing drugs.
The cytoplasm describes all the material within a eukaryotic or prokaryotic cell, enclosed by the cell membrane, including the organelles [1] and excluding the nucleus in eukaryotic cells. The material inside the nucleus of a eukaryotic cell and contained within the nuclear membrane is termed the nucleoplasm .
Cell Biology in "The Biology Project" of University of Arizona. Centre of the Cell online; The Image & Video Library of The American Society for Cell Biology Archived 2011-06-10 at the Wayback Machine, a collection of peer-reviewed still images, video clips and digital books that illustrate the structure, function and biology of the cell.
Examples of real images include the image produced on a detector in the rear of a camera, and the image produced on an eyeball retina (the camera and eye focus light through an internal convex lens). In ray diagrams (such as the images on the right), real rays of light are always represented by full, solid lines; perceived or extrapolated rays ...
Moreover, live-cell imaging often employs special optical system and detector specifications. For example, ideally the microscopes used in live-cell imaging would have high signal-to-noise ratios, fast image acquisition rates to capture time-lapse video of extracellular events, and maintaining the long-term viability of the cells. [26]
Light micrograph of a moss's leaf cells at 400X magnification. The following outline is provided as an overview of and topical guide to cell biology: . Cell biology – A branch of biology that includes study of cells regarding their physiological properties, structure, and function; the organelles they contain; interactions with their environment; and their life cycle, division, and death.
For example, a common application of cytopathology is the Pap smear, a screening test used to detect cervical cancer, and precancerous cervical lesions that may lead to cervical cancer. [ 33 ] Cell cycle checkpoints and DNA damage repair system
Note: Cytoplasm of this cell or the neighboring cell is not visible (top-left), which is currently in the telophase of mitosis. Image taken using an optical microscope and DAPI staining of DNA. Interphase is the active portion of the cell cycle that includes the G1 , S , and G2 phases, where the cell grows , replicates its DNA , and prepares ...