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Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon. [1] [2] [3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid). [2] It is prescribed for the treatment of pink eye in combination with ...
Corneal abrasion is a scratch to the surface of the cornea of the eye. [3] Symptoms include pain, redness, light sensitivity, and a feeling like a foreign body is in the eye. [1] Most people recover completely within three days. [1] Most cases are due to minor trauma to the eye such as that which can occur with contact lens use or from ...
Corneal ulcer, also called keratitis, is an inflammatory or, more seriously, infective condition of the cornea involving disruption of its epithelial layer with involvement of the corneal stroma. [ 1 ] [ 2 ] [ 3 ] It is a common condition in humans particularly in the tropics and in farming. [ 4 ]
Over time, it has been reported that many of the same drugs and eye drops used to treat particular eye diseases do, in fact, result in systemic side effects that could possibly be minimized or limited due to a slower, more sustained release of the drug. The systemic side effects of glaucoma medications such as latanoprost increased heart rate ...
Prednisolone eye drops are used in conjunctivitis caused by allergies and bacteria, marginal keratitis, uveitis, endophthalmitis, which is an infection of the eye involving the aqueous humor, Graves' ophthalmopathy, herpes zoster ocular infection, inflammation of the eye after surgery, and corneal injuries caused by chemicals, radiation ...
Uveitis is typically treated with glucocorticoid steroids, either as topical eye drops (prednisolone acetate) or as oral therapy. [27] Prior to the administration of corticosteroids, corneal ulcers must be ruled out. This is typically done using a fluorescence dye test. [28]
An oral tetracycline antibiotic (such as doxycycline) may be used in systemic or particularly severe/intractable infections. [2] [4] Erythromycin may be an effective alternative, especially in pediatric cases where the side effects of tetracyclines are unacceptable. [4] Artificial tears can reduce dryness and discomfort from corneal lesions. [2]
A study with patients receiving loteprednol eye drops over 42 days showed no adrenal suppression, which would be a sign of the drug reaching the bloodstream to a clinically relevant extent. [2] Steroid receptor affinity was 4.3 times that of dexamethasone in animal studies. [2]
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