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These cutting-edge models are poised to revolutionize therapeutic drug monitoring and forecasting for patients undergoing transplantation and immunosuppressive therapy.
Therapeutic drug monitoring (TDM) aims to optimize treatments by individualizing dosage regimens based on the measurement of blood concentrations. Dosage individualization to maintain concentrations within a target range requires pharmacokinetic and clinical capabilities.
TDMx is a model-informed precision dosing (MIPD) software to bring state-of-the-art pharmacometrics to T herapeutic Drug Monitoring (TDM), thereby being very user-friendly. No technical pharmacometrics or modeling skills are required to use TDMx.
We offer a large number and variety of analytes at multiple levels to monitor the precision of therapeutic drug testing procedures. All our therapeutic quality controls are for general TDM testing needs.
Therapeutic drug monitoring (TDM) aims to optimize treatments by individualizing dosage regimens based on the measurement of blood concentrations. Dosage individualization to maintain concentrations within a target range requires pharmacokinetic and clinical capabilities.
Model-informed precision dosing (MIPD) is an emerging dosing paradigm in which mathematical models are used for dose optimization, using individual information such as a patient’s age, organ function, and the results of therapeutic drug monitoring.
Therapeutic Drug Monitoring (TDM) is a valuable tool used in clinical practice to optimize medication therapy and ensure that drug levels in a patient’s body are within the therapeutic range.
In conclusion, TDM in pediatrics represents, similarly to adults, a useful tool that allows a more tailored drug administration and, therefore, the individualization of therapy to avoid risks of therapeutic failures or drug toxicity.
Objective: Nomograms, equations and pharmacokinetic software are considered the main tools available for therapeutic drug monitoring. Due to its great applicability to various groups of drugs, the use of software is widely extended in clinical practice.
The present study aimed tosynthesize the available evidence regarding software applied to therapeutic drug monitoring to facilitate its identification, evaluation and election by users, and synthesized the most relevant characteristics of the pharmacokinetic software available.