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Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting. [12] [1] It is also sometimes used before surgery to decrease saliva. [1]
Hyoscine butylbromide, also known as scopolamine butylbromide [4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic.
Scopolamine is a nonspecific muscarinic antagonist at all four (M 1, M 2, M 3, and M 4) receptor sites. [ 10 ] [ 11 ] Due to these compounds' inhibition of various signal transduction pathways, the decrease in acetylcholine signaling is what leads to many of the cognitive deficits and mental impairments.
Hyoscyamine and scopolamine are present and labeled in the diagram. Hyoscyamine can be extracted from plants of the family Solanaceae , notably Datura stramonium . As hyoscyamine is a direct precursor in the plant biosynthesis of hyoscine , it is produced via the same metabolic pathway .
Anticholinergic drugs [8] and deliriants: [9]. Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna); Hyoscyamine, the levo-isomer of atropine, from henbane (Hyoscyamus niger), mandrake (Mandragora officinarum) and the sorcerers' tree (Latua pubiflora).
GLP-1 agonists like Ozempic have exploded over the past few years, thanks to data that show they can help people lose a significant amount of weight. But these medications aren’t perfect, and it ...
Three types of medications are sometimes prescribed to improve symptoms of motion sickness: antimuscarinics such as scopolamine, H 1 antihistamines such as dimenhydrinate, and amphetamines such as dexamphetamine. [3] Benefits are greater if used before the onset of symptoms or shortly after symptoms begin. [2]
Dr. Lopez says that if the doctor believes you are a good fit for weight loss medication, they will give you a prescription and schedule follow-up appointments to track your progress and make any ...