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Acid dissociation constants are also essential in aquatic chemistry and chemical oceanography, where the acidity of water plays a fundamental role. In living organisms, acid–base homeostasis and enzyme kinetics are dependent on the p K a values of the many acids and bases present in the cell and in the body.
As a reagent in organic chemistry, DBU is used as a ligand and base. As a base, protonation occurs at the imine nitrogen. [5] Lewis acids also attach to the same nitrogen. [6] These properties recommend DBU for use as a catalyst, for example as a curing agent for epoxy resins and polyurethane.
The buffering region is dependent upon the pKa, and is typically +/- 1.0 pH units of the pKa. The pKa of KHP is 5.4, so its pH buffering range would be 4.4 to 6.4; however, due to the presence of the second acidic group that bears the potassium ion, the first pKa also contributes to the buffering range well below pH 4.0, which is why KHP is a ...
1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) is a chemical compound with the formula C 7 H 12 N 2. [1] It is an amidine base used in organic synthesis. A related compound with related functions is 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). The relatively complex nature of the formal names for DBU and DBN (hence the common use of acronyms) reflects the ...
In computational biology, protein pK a calculations are used to estimate the pK a values of amino acids as they exist within proteins.These calculations complement the pK a values reported for amino acids in their free state, and are used frequently within the fields of molecular modeling, structural bioinformatics, and computational biology.
The methylsilyl groups give KHMDS good solubility in most organic solvents. Solution structures are either solvated monomers or dimers (or mixtures thereof) with this depending on the coordinating power, concentration, and temperature of the solvent. [3]
PKA may refer to: Napaskiak Airport (IATA code), airport in Napaskiak, Alaska; Professionally known as: Pen name; Stage persona; pK a, the symbol for the acid dissociation constant at logarithmic scale; Protein kinase A, a class of cAMP-dependent enzymes; Pi Kappa Alpha, the North-American social fraternity
Pentafluorobenzoic acid (PFBA) is an organofluorine compound with the formula C 6 F 5 CO 2 H. It is a white crystalline powder that has a high solubility in water. Its pK a of 1.48 indicates that it is a strong acid. [1]