Search results
Results From The WOW.Com Content Network
Friedel–Crafts alkylations can be reversible. Although this is usually undesirable it can be exploited; for instance by facilitating transalkylation reactions. [10] 1,3-Diisopropylbenzene is produced via transalkylation, a special form of Friedel–Crafts alkylation. It also allows alkyl chains to be added reversibly as protecting groups.
This reaction is typically catalyzed by the corresponding iron or aluminum trihalide. The Friedel–Crafts reaction can be performed either as an acylation or as an alkylation. Often, aluminium trichloride is used, but almost any strong Lewis acid can be applied. For the acylation reaction a stoichiometric amount of aluminum trichloride is ...
Freund reaction; Friedel–Crafts acylation; Friedel–Crafts alkylation; Friedländer synthesis; ... This page was last edited on 11 November 2024, at 16:27 (UTC).
In addition to the ordinary thermal phenyl ester reaction a photochemical variant is possible. The photo-Fries rearrangement can likewise give [1,3] and [1,5] products, [7] [8] which involves a radical reaction mechanism. This reaction is also possible with deactivating substituents on the aromatic group. Because the yields are low this ...
In electrophilic substitution in aromatic compounds, an atom appended to the aromatic ring, usually hydrogen, is replaced by an electrophile.The most important reactions of this type that take place are aromatic nitration, aromatic halogenation, aromatic sulfonation and acylation and alkylating Friedel-Crafts reactions.
The reaction is a type of Friedel-Crafts acylation with hydrogen chloride and a Lewis acid catalyst. The synthesis of 2,4,6-Trihydroxyacetophenone (THAP) from phloroglucinol is representative: [1] If two-equivalents are added, 2,4-Diacetylphloroglucinol is the product. Hoesch reaction example, 1-(2,4,6-trihydroxyphenyl)ethanone from phloroglucinol
Friedel–Crafts reaction, a type of organic reaction developed by Charles Friedel and James Crafts in 1877. Friedel's law, named after Georges Friedel, the crystallographer, is a property of Fourier transforms of real functions.
A native of Strasbourg, France, he was a student of Louis Pasteur at the Sorbonne.In 1876, he became a professor of chemistry and mineralogy at the Sorbonne.. Friedel developed the Friedel-Crafts alkylation and acylation reactions with James Crafts in 1877, [2] [3] and attempted to make synthetic diamonds.